On the theoretical basis of perfusion measurements by dynamic susceptibility contrast MRI

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On the theoretical basis of perfusion measurements by dynamic susceptibility contrast MRI.

A quantitative analysis was undertaken to calibrate the perfusion quantification technique based on tracking the first pass of a bolus of a blood pool contrast agent. A complete simulation of the bolus passage, of the associated changes in the T2 and T2* signals, and of the data processing was performed using the tracer dilution theory, an analytical theory of the MR signal from living tissues ...

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Perfusion measurements by dynamic susceptibility MRI

List of Papers This thesis is based on the following papers, which are referred to in the text by their Roman numerals. Abbreviations ADC Apparent diffusion coefficient AIF Arterial input function ASL Arterial spin labeling CBF Cerebral blood flow CBV Cerebral blood volume CPB Cardio pulmonary bypass DSC-MRI Dynamic susceptibility contrast MRI MRI Magnetic resonance imaging MRS Magnetic resonan...

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Dynamic susceptibility contrast perfusion MRI (with pitfalls)

Since the first studies in the late 1980s and early 1990s, dynamic susceptibility contrast MRI (DSC-MRI, also known as ‘bolus tracking’) has become a very powerful technique for the assessment of perfusion, and perfusion-related parameters (see (1,2) for recent reviews). Despite the need of an exogenous MR agent (cf. arterial spin labeling techniques), DSC-MRI is currently the most common MR pe...

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Dynamic susceptibility contrast MRI

Introduction Quantitative dynamic susceptibility contrast perfusion MRI (DSC-MRI) is based on the monitoring of the first passage of a bolus of contrast agent through the brain tissue and a brain-feeding artery. The contrast agent is injected rapidly by means of an MRinjector in the antecubital vein in the patients arm and a saline flush is used to push the contrast agent into the direction of ...

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Crossed Cerebellar Diaschisis in Acute Isolated Thalamic Infarction Detected by Dynamic Susceptibility Contrast Perfusion MRI

PURPOSE Crossed cerebellar diaschisis (CCD) is a state of neural depression caused by loss of connections to injured neural structures remote from the cerebellum usually evaluated by positron emission tomography. Recently it has been shown that dynamic susceptibility contrast perfusion weighted MRI (PWI) may also be feasible to detect the phenomenon. In this study we aimed to assess the frequen...

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ژورنال

عنوان ژورنال: Magnetic Resonance in Medicine

سال: 2001

ISSN: 0740-3194,1522-2594

DOI: 10.1002/mrm.1307